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Hep 2 Cells | namal | 2007-09-05 | Click here to register. |
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| I want some information about Hep2 cells .Is it a cancer cell line? If so what is it origin? | | |
| JAR | 2007-09-09 | Click here to register. |
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 | Hep2 cells are actually HeLa cells. This is a very old cell line that came from a cervical tumor that killed the patient. For more information check out www.ATCC.org or google Hela. |
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| seanpeel | 2007-09-13 | Click here to register. |
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| The HEp-2 cell line was established in 1952 by A. E. Moore, L. Sabachewsky, and H. W. Toolan (Cancer Res. 15: 598, 1955) from tumors that had been produced in irradiated-cortisonized weanling rats after injection with epidermoid carcinoma tissue from the larynx of a 56-year-old male (H. Toolan, Cancer Res. 14: 660, 1954). A hardy cell line, HEp-2 resists temperature, nutritional, and environmental changes without a loss of viability. It has supported growth of 10 of 14 arboviruses (Texas Rep. Biol. Med. 15: 588, 1957) and measles virus (Proc. Soc. Exp. Biol. Med. 93: 107, 1956), and it has been used for experimental studies of tumor production in rats, hamsters, mice, embryonated eggs and volunteer terminal cancer patients (Ann. N.Y. Acad. Sci. 76: 497, 1958).
(see http://www.viromed.com/services/product/hep2.htm)
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| JAR | 2007-10-25 | Click here to register. |
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| It is actually a substrain from HeLa. It has an identical DNA fingerprint and has been HeLa from the very start. There are no Hep2 cells in existance that are not derived from hela. It was first shown to be hela in 1967 and is still widely used for virus detection. |
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